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Gout > Follow-up Author: Grace P. Teal, MD; Howard A. Fuchs, MD
Editorial changes - 2009-09-02
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Prevention
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Rationale:

  • Uric acid levels should generally be <6 mg/dL for effective management.
  • Uric acid levels will reach steady state about 2 weeks after uric acid-lowering medications are instituted or changed.

Evidence:

  • A retrospective study discusses the optimal range of serum urate concentrations to minimize risk for gout attacks during antihyperuricemic treatment (54).
  • A controlled clinical trial compared treatment with allopurinol and probenecid (75).

Comments:

  • None.

FAQs
Grace P. Teal, MD (deceased) has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Howard A. Fuchs, MD, is a consultant for TAP Pharmaceuticals.
Steven E. Weinberger, MD, FACP, Acting Editor, PIER, has stock holdings in Glaxosmithkline and Abbott.


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