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Rationale:
- All medications used to treat gout could have substantial side effects that necessitate ongoing monitoring. Blood counts and
renal function may decrease at any time during therapy and need regular monitoring.
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Evidence:
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Comments:
- Patients with renal insufficiency are at much higher risk for hypersensitivity reactions (allopurinol), further decline in
renal function (NSAIDs), marrow injury (allopurinol and colchicine), and neurologic effects (colchicine).
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Grace P. Teal, MD (deceased) has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Howard A. Fuchs, MD, is a consultant for TAP Pharmaceuticals.
Darren B. Taichman, MD, PhD, Editor, PIER, has received grant support from Actelion Pharmaceuticals Ltd , and honoraria for
continuing medical education grand rounds and lectures given.
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The information included herein should never be used as a substitute
for clinical judgment and does not represent an official position of
ACP. Because all PIER modules are updated regularly, printed web pages
or PDFs may rapidly become obsolete. Therefore, PIER users should
compare the date of the last update on the website with any printout
to ensure that the information being referred to is the most current
available.
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PIER is copyrighted (c) 2010 by the American College of Physicians,
190 N. Independence Mall West, Philadelphia, PA 19106-1572, USA.
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Gout
> Patient Education
