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Rationale:
- The medication benefits for PTSD usually are moderate under the best of circumstances.
- Psychiatric consultation can assist with optimization of drug therapy for nonresponders and patients with coexisting illnesses.
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Evidence:
- A number of studies, including controlled trials, support the efficacy of SSRIs and other antidepressants for reducing symptoms
of PTSD (1; 24; 25; 26; 27; 28; 29; 30), but complete symptom resolution is uncommon.
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Comments:
- The tenacious nature of PTSD symptoms and their common coexistence with other psychiatric disorders may make medication management
difficult, especially with limited research data to guide second- and third-line strategies.
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Jeffrey P. Staab, MD, MS, is a consultant for Eli Lilly, Forest Laboratories, received honorarium from Abbott Laboratories, received grants from GlaxoSmithKline,
Pfizer. Michael Roy, MD, editorial consultant, received honorarium from PFizer.
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The information included herein should never be used as a substitute
for clinical judgment and does not represent an official position of
ACP. Because all PIER modules are updated regularly, printed web pages
or PDFs may rapidly become obsolete. Therefore, PIER users should
compare the date of the last update on the website with any printout
to ensure that the information being referred to is the most current
available.
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PIER is copyrighted (c) 2008 by the American College of Physicians,
190 N. Independence Mall West, Philadelphia, PA 19106-1572, USA.
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Posttraumatic Stress Disorder
> Consultation for Management
