Diabetes Mellitus, Type 1 Author: Maureen D. Passaro, MD; Robert E. Ratner, MD
Editorial changes - 2012-04-30
Author information and module status
Prevention
Screening
Diagnosis
Consultation for Diagnosis
Hospitalization
Therapy
Patient Education
Consultation for Management
Follow-up

Tables
Figures
References
Glossary
What's New
Patient Information
Additional Resources
Tools

Quality Measures Quality Measures
What's New
Alert
2012-04-20FDA Safety Alert for Aliskiren-containing Medications: Drug Safety Communication - New Warning and Contraindication
2011-03-29FDA Safety Alert for Roche ACCU-CHEK FlexLink Plus Infusion Set: Class I Recall - Potential for Under-Delivery of Insulin
2010-08-26FDA Safety Alert for Fingerstick Devices to Obtain Blood Specimens: Initial Communication - Risk of Transmitting Bloodborne Pathogens
2010-01-26FDA Announces Class I Recall of Certain Infusion Set Needles
2010-01-22Nipro Medical Corporation Issues a Voluntary Recall of All GlucoPro Insulin Syringes
2009-08-24FDA MedWatch Safety Alert for Accusure Insulin Syringes [31G, 1/2 cc and 1 cc]
2009-04-30Disetronic Medical Systems Inc. (a member of the Roche Group) announces a recall (field corrective action) of the ACCU-CHEK® Spirit insulin pump due to “up” and/or “down” button failures

New Information
2010-01-20Standards of Medical Care in Diabetes - 2010

New Information from ACP
2012-01-03Annals of Internal Medicine Evaluation of Guideline Recommendations on Oral Medications for Type 2 Diabetes Mellitus
2011-09-06Annals of Internal Medicine Lifestyle Factors and Risk for New-Onset Diabetes
2011-05-03Annals of Internal Medicine Comparative Effectiveness and Safety of Medications for Type 2 Diabetes: An Update Including New Drugs and 2-Drug Combinations
2011-03-01Annals of Internal Medicine Racial Differences in Glycemic Markers: A Cross-sectional Analysis of Community-Based Data
2011-02-15Annals of Internal Medicine Intensive Insulin Therapy in Hospitalized Patients: A Systematic Review
2011-02-15Annals of Internal Medicine Use of Intensive Insulin Therapy for the Management of Glycemic Control in Hospitalized Patients: A Clinical Practice Guideline From the American College of Physicians
2010-12-21Annals of Internal Medicine Trans-Palmitoleic Acid, Metabolic Risk Factors, and New-Onset Diabetes in U.S. Adults
2010-06-15Annals of Internal Medicine Glucose-Independent, Black–White Differences in Hemoglobin A1c Levels

Newly Cited References
2011-12-01Effect of educational components and strategies associated with insulin pump therapy: a systematic review.
2011-11-17Review Topic on Management of Endocrine Disease: Beneficial effect of real-time continuous glucose monitoring system on glycemic control in type 1 diabetic patients: systematic review and meta-analysis of randomized trials.
2011-11-08The worldwide epidemiology of type 2 diabetes mellitus-present and future perspectives.
2011-10-01Continuous glucose monitoring: an Endocrine Society Clinical Practice Guideline.
2011-09-22High-dose statin pretreatment for the prevention of contrast-induced nephropathy: a meta-analysis.
2011-09-13Acetylcysteine for prevention of renal outcomes in patients undergoing coronary and peripheral vascular angiography: main results from the randomized Acetylcysteine for Contrast-induced nephropathy Trial (ACT).
2011-07-07Glycaemic control in type 1 diabetes during real time continuous glucose monitoring compared with self monitoring of blood glucose: meta-analysis of randomised controlled trials using individual patient data.
2011-07-01Effects of intensive blood pressure reduction on myocardial infarction and stroke in diabetes: a meta-analysis in 73,913 patients.
2011-06-01Position statement executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.
2011-03-14Long-term renal outcomes of patients with type 1 diabetes mellitus and microalbuminuria: an analysis of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications cohort.
2011-03-01Insulin degludec in type 1 diabetes: a randomized controlled trial of a new-generation ultra-long-acting insulin compared with insulin glargine.
2011-02-15Intensive insulin therapy in hospitalized patients: a systematic review.
2011-02-01Urinary C-peptide creatinine ratio is a practical outpatient tool for identifying hepatocyte nuclear factor 1-alpha
2011-01-19Statins for the primary prevention of cardiovascular disease.
2011-01-01Standards of medical care in diabetes--2011.
2010-07-01Glycemic control and cardiovascular disease in 7,454 patients with type 1 diabetes: an observational study from the Swedish National Diabetes Register (NDR).
2010-04-15Short-term case fatality rate and associated factors among inpatients with diabetic ketoacidosis and hyperglycemic hyperosmolar state: a hospital-based analysis over a 15-year period.
2010-02-01Point-of-care testing for patients with diabetes, hyperlipidaemia or coagulation disorders in the general practice setting: a systematic review.
2009-11-03Systematic review: sodium bicarbonate treatment regimens for the prevention of contrast-induced nephropathy.
2009-07-01International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes.
2009-01-14Diabetic nephropathy.
2008-10-16The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease.
2008-09-01NICE guidance on diabetes in pregnancy: management of diabetes and its complications from preconception to the postnatal period. NICE clinical guideline 63. London, March 2008.
2008-01-12Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis.
2007-04-18Long-acting insulin analogues versus NPH insulin (human isophane insulin) for type 2 diabetes mellitus.
2005-12-22Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes.
2005-07-21Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis.
2004-04-17Risk of complications of pregnancy in women with type 1 diabetes: nationwide prospective study in the Netherlands.
2004-01-01Diabetes patient education: a meta-analysis and meta-regression.
2004-01-01Retinopathy in diabetes.
2004-01-01Physical activity/exercise and diabetes.
2004-01-01Nephropathy in diabetes.
2002-12-17Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report.
2002-08-01Influence of age on the presentation and outcome of acidotic and hyperosmolar diabetic emergencies.
2002-07-01American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for developing a diabetes mellitus comprehensive care plan.
2002-07-01Effect of dietary protein restriction on prognosis in patients with diabetic nephropathy.
2001-03-06Should all patients with type 1 diabetes mellitus and microalbuminuria receive angiotensin-converting enzyme inhibitors? A meta-analysis of individual patient data.
2001-01-25Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics.
2000-01-22Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators.
1999-11-01Smoking and diabetes.
1999-09-01Benefits of a multidisciplinary approach in the management of recurrent diabetic foot ulceration in Lithuania: a prospective study.
1997-09-01Novel forms of insulin delivery.
1996-09-01Photocoagulation for diabetic macular edema: Early Treatment Diabetic Retinopathy Study Report no. 4. The Early Treatment Diabetic Retinopathy Study Research Group.
1996-09-01Association of elevated serum lipid levels with retinal hard exudate in diabetic retinopathy. Early Treatment Diabetic Retinopathy Study (ETDRS) Report 22.
1996-06-01Cigarette smoking and progression of retinopathy and nephropathy in type 1 diabetes.
1994-08-01Exercise in individuals with IDDM.
1994-07-01The acute effect of smoking on retinal blood flow in subjects with and without diabetes.
1994-07-01Hypoglycemia.
1994-01-01Diabetic ketoacidosis and the hyperglycemic hypersomolar nonketotic state.
1993-05-22Meta-analysis of effects of intensive blood-glucose control on late complications of type I diabetes.
1992-07-15Risk factors for amputation in patients with diabetes mellitus. A case-control study.
1991-02-06Cigarette smoking increases the risk of albuminuria among subjects with type I diabetes.
1990-05-01Pathways to diabetic limb amputation. Basis for prevention.
1990-04-01Cigarette smoking and neuropathy in diabetic patients.
1989-11-01Is blood pressure a predictor of the incidence or progression of diabetic retinopathy?
1988-04-01Clinical aspects of exercise and diabetes mellitus.
1988-04-01Hyperglycemia after intense exercise in IDDM subjects during continuous subcutaneous insulin infusion.
1988-02-01Atherosclerosis and physical activity.
1988-02-01Role and management of exercise in diabetes mellitus.
1985-12-01Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1. Early Treatment Diabetic Retinopathy Study research group.
1985-04-01Diabetic retinopathy as detected using ophthalmoscopy, a nonmydriatic camera and a standard fundus camera.
1978-01-01Photocoagulation treatment of proliferative diabetic retinopathy: the second report of diabetic retinopathy study findings.

New References of Interest
2012-04-21Insulin degludec, an ultra-longacting basal insulin, versus insulin glargine in basal-bolus treatment with mealtime insulin aspart in type 1 diabetes (BEGIN Basal-Bolus Type 1): a phase 3, randomised, open-label, treat-to-target non-inferiority trial.
2012-02-02GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus.
2012-01-23Statin use and risk of diabetes mellitus in postmenopausal women in the Women's Health Initiative.
2012-01-07Effectiveness of diabetes and hypertension management by rural primary health-care workers (Behvarz workers) in Iran: a nationally representative observational study.
2012-01-01Management of hyperglycemia in hospitalized patients in non-critical care setting: an endocrine society clinical practice guideline.
2011-12-23Use of hepatitis B vaccination for adults with diabetes mellitus: recommendations of the Advisory Committee on Immunization Practices (ACIP).
2011-12-22Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes.
2011-12-12The effect of a structured behavioral intervention on poorly controlled diabetes: a randomized controlled trial.
2011-12-12Evaluation of a behavior support intervention for patients with poorly controlled diabetes.
2011-11-28Association between glycemic control and adverse outcomes in people with diabetes mellitus and chronic kidney disease: a population-based cohort study.
2011-10-24Cardiovascular Risk Prediction in Diabetic Men and Women Using Hemoglobin A1c vs Diabetes as a High-Risk Equivalent.
2011-09-26Encounter frequency and serum glucose level, blood pressure, and cholesterol level control in patients with diabetes mellitus.
2011-09-12Team-based care approach to cholesterol management in diabetes mellitus: 2-year cluster randomized controlled trial.
2011-09-09Time trends in mortality in patients with type 1 diabetes: nationwide population based cohort study.
2011-08-06Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial.
2011-07-30Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial.
2011-07-23Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial.
2011-07-09Glycaemic control and incidence of heart failure in 20,985 patients with type 1 diabetes: an observational study.
2011-07-08Factors associated with the presence of diabetic ketoacidosis at diagnosis of diabetes in children and young adults: a systematic review.
2011-06-22Temporal trends in the prevalence of diabetic kidney disease in the United States.
2011-04-15Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies.
2011-04-11Evidence-based guideline: Treatment of painful diabetic neuropathy: Report of the American Academy of Neurology, the American Association of Neuromuscular and Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation.
2011-03-14Impact of diabetes on cardiovascular disease risk and all-cause mortality in older men: influence of age at onset, diabetes duration, and established and novel risk factors.
2011-03-10Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes.
2011-03-03Diabetes mellitus, fasting glucose, and risk of cause-specific death.
2011-02-15Use of Intensive Insulin Therapy for the Management of Glycemic Control in Hospitalized Patients: A Clinical Practice Guideline From the American College of Physicians.
2011-02-04Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies.
2011-01-24Albuminuria and decline in cognitive function: The ONTARGET/TRANSCEND studies.
2010-08-11Prevalence of diabetic retinopathy in the United States, 2005-2008.
2010-07-22Effectiveness of sensor-augmented insulin-pump therapy in type 1 diabetes.
2010-07-10Diabetic retinopathy.
2010-07-07Tight blood pressure control and cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease.
2010-06-28Variation in the net benefit of aggressive cardiovascular risk factor control across the US population of patients with diabetes mellitus.
2010-06-26Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.
2010-06-14Prognostic implications of the urinary albumin to creatinine ratio in veterans of different ages with diabetes.
2010-05-17Glycated haemoglobin A1c for diagnosing diabetes in Chinese population: cross sectional epidemiological survey.
2010-04-28Effect of B-vitamin therapy on progression of diabetic nephropathy: a randomized controlled trial.
2010-02-01Correlates of insulin injection omission.
2009-11-06Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trials.
2009-08-10Diabetes mellitus in long-term survivors of childhood cancer. Increased risk associated with radiation therapy: a report for the childhood cancer survivor study.
FAQs
Abd A. Tahrani, MD, MRCP, editorial consultant, has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Maureen D. Passaro, MD has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Robert E. Ratner, MD has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Deborah Korenstein, MD, FACP, Co-Editor, PIER, has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Richard B. Lynn, MD, FACP, Co-Editor, PIER, has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.


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