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Rationale:
- Generally, random plasma glucose levels are not considered diagnostic and should not serve as a screening test for type 2
diabetes; however, in instances in which patients are found to have elevations in random plasma glucose levels, further testing
for diabetes may be warranted.
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Evidence:
- Patients with mild-to-moderate elevations of random blood sugar (glucose >126 mg/dL but less than the diagnostic 200 mg/dL)
are at elevated risk for developing overt type 2 diabetes (54); these patients might have impaired glucose tolerance or impaired fasting glucose (55).
- Furthermore, the risk of microvascular complications is associated strongly with elevated blood-glucose levels (22).
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Comments:
- Because of the elevated risk and increased likelihood of benefit in this population, periodic monitoring for the development
of diabetes might be warranted.
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Sandeep Vijan, MD has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Darren B. Taichman, MD, PhD, Editor, PIER, has received grant support from Actelion Pharmaceuticals Ltd , and honoraria for
continuing medical education grand rounds and lectures given.
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PIER is copyrighted (c) 2010 by the American College of Physicians,
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