Diabetic Ketoacidosis Author: Heather Lochnan, MD
Approved for review - 2009-03-25
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Prevention
Screening
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Screening
  • Screen all patients with moderate to severely elevated blood sugars (≥350 mg/dL).
  • Consider diabetic ketoacidosis in patients with an anion gap metabolic acidosis.
  • Consider DKA in diabetes mellitus patients with infection, CVA, MI, or other illness.
  • Consider DKA in diabetic patients with symptoms of nausea and vomiting, even if blood glucose is <250 mg/dL.
  • Consider DKA in patients on atypical antipsychotics who present with hyperglycemia.


Screen all patients with moderate to severely elevated blood sugars (≥350 mg/dL). C

  • Measure electrolytes and blood gases to determine whether anion gap metabolic acidosis is present in patients with positive ketones, constitutional symptoms, or suspicion of DKA.
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Consider diabetic ketoacidosis in patients with an anion gap metabolic acidosis. BC

  • Measure serum glucose in patients with metabolic acidosis.
Background | Back to top


Consider DKA in diabetes mellitus patients with infection, CVA, MI, or other illness. AB

  • Measure serum or capillary glucose and if >250 mg/dL, check the patient's electrolyte and ketone levels and anion gap.
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Consider DKA in diabetic patients with symptoms of nausea and vomiting, even if blood glucose is <250 mg/dL. BC

  • Measure electrolyte and ketone levels and determine anion gap in patients with diabetes and normal sugar levels if symptoms suggest DKA despite normal blood sugar levels.
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Consider DKA in patients on atypical antipsychotics who present with hyperglycemia. C

  • Measure anion gap and ketones in patients on atypical antipsychotics who present with moderate to severe hyperglycemia.
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FAQs
Ebenezer A. Nyenwe, MD, editorial consultant, has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Heather Lochnan, MD has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Steven E. Weinberger, MD, FACP, Acting Editor, PIER, has stock holdings in Glaxosmithkline and Abbott.


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