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Nerve Agent Exposure > Drug Therapy Author: Elliot Rodriguez, MD, FACEP; Christine M. Stork, PharmD, DABAT
Editorial changes - 2011-12-08
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Rationale:

  • Atropine competitively inhibits muscarinic cholinergic effects, the most life-threatening of which is bronchorrhea and bronchospasm.

Evidence:

  • Multiple case series reporting on the Tokyo subway sarin attack describe alleviation of symptoms after treatment with atropine (24; 25; 26; 27).

Comments:

  • None.

FAQs
Christine M. Stork, PharmD, DABAT has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Elliot Rodriguez, MD, FACEP has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Jerrold B. Leikin, MD, editorial consultant, has testified on the effects of carbon monoxide exposure in civil courts.
Deborah Korenstein, MD, FACP, Co-Editor, PIER, has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Richard B. Lynn, MD, FACP, Co-Editor, PIER, has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.


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