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Nerve Agent Exposure > Prevention Author: Elliot Rodriguez, MD, FACEP; Christine M. Stork, PharmD, DABAT
Editorial changes - 2009-12-01
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Rationale:

  • Preventing bodily contact with nerve agent vapor or liquid will prevent symptoms from occurring.

Evidence:

  • A review and opinion article recommends that medical personnel performing patient decontamination at a hospital should use, at minimum, Level C personal protective equipment (1).
  • Multiple case series and reports show that on-scene rescue personnel and hospital-based healthcare workers who do not wear protective equipment are at risk for secondary exposure to nerve agents from contaminated or inadequately decontaminated patients (2; 3; 4).

Comments:

  • Butyl rubber gloves are required because latex is permeable to nerve agents.
  • Distribution of personal protective equipment, specifically face masks, to the general population as occurred in Israel during the first Gulf War was associated with morbidity and deaths (5).

FAQs
Christine M. Stork, PharmD, DABAT has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Elliot Rodriguez, MD, FACEP has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Jerrold B. Leikin, MD, editorial consultant, received royalties from McGraw-Hill, Taylor and Francis; editor of Toxicoterrorism (McGraw-Hill).
Darren B. Taichman, MD, PhD, Editor, PIER, has received grant support from Actelion Pharmaceuticals Ltd , and honoraria for continuing medical education grand rounds and lectures given.


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