Nerve Agent Exposure Author: Elliot Rodriguez, MD, FACEP; Christine M. Stork, PharmD, DABAT
Editorial changes - 2009-10-30
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Prevention
  • Use specialized personal protective garb and mask for protection against exposure to nerve agents.
  • Consider the use of pyridostigmine bromide before nerve agent exposure.
  • Consider the use of topical skin protectant before nerve agent exposure.


Use specialized personal protective garb and mask for protection against exposure to nerve agents. C

  • Ensure that personnel performing decontamination or providing medical care at a site away from the primary contamination site use chemical-resistant suits, butyl rubber gloves and boots, as well as self-contained breathing apparatus (Level B protection) or a full-face air purification device (Level C protection).
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Consider the use of pyridostigmine bromide before nerve agent exposure. C

  • Consider beginning pyridostigmine bromide tablets, 30 mg, every 8 hours when exposure to soman is thought to be imminent.
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Consider the use of topical skin protectant before nerve agent exposure. C

  • Consider topical SERPACWA, a 50:50 paste-like mixture of perfluoroalkylpolyether and polytetrafluoroethylene, used in conjunction with personal protective equipment.
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FAQs
Christine M. Stork, PharmD, DABAT has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Elliot Rodriguez, MD, FACEP has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Jerrold B. Leikin, MD, editorial consultant, received royalties from McGraw-Hill, Taylor and Francis; editor of Toxicoterrorism (McGraw-Hill).
Steven E. Weinberger, MD, FACP, Acting Editor, PIER, has stock holdings in Glaxosmithkline and Abbott.


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