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West Nile Virus Disease > Diagnosis Author: Amy V. Bode, MD, MSPH; James J. Sejvar, MD; Anthony A. Marfin, MD, MPH
Editorial changes - 2009-06-03
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Rationale:

  • WNV is a mosquito-transmitted flavivirus, and activity in birds and horses has preceded human cases.
  • WNV can be transmitted through blood products and organ transplantation.

Evidence:

  • In the U.S., dead bird-based surveillance has been used to track virus activity, and dead bird clusters may predict human outbreaks (22).
  • A total of 30 patients have been documented to have acquired WNV from blood transfusion (19).
  • WNV has been transmitted through organ transplantation in two separate case reports of four patients (8; 9).

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Amy V. Bode, MD, MSPH has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Anthony A. Marfin, MD, MPH has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. James J. Sejvar, MD has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Yanlin Tang, PhD, editorial consultant, has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Darren B. Taichman, MD, PhD, Editor, PIER, has received grant support from Actelion Pharmaceuticals Ltd , and honoraria for continuing medical education grand rounds and lectures given.

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