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Rationale:
- CSF pleocytosis (30 to 100 cells/µL) with lymphocytosis and elevated protein (80 to 105 mg/dL) with normal glucose are seen
in some patients with WNV meningitis, encephalitis, or other neuroinvasive syndromes.
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Evidence:
- CSF pleocytosis (range, 0 to 2300 cells/m3) was seen in both a 1999 New York case series and a 2002 Louisiana case series (26; 30).
- Increased CSF protein was seen in a 2000 Israeli series, a 2002 Canadian case series (range, 30 to 200 mg/dL), and a 2002
Louisiana case series (range, 40 to 234 mg/dL) (24; 29; 30).
- Normal CSF glucose was seen in a 2000 New York and New Jersey case series (32).
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Comments:
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Amy V. Bode, MD, MSPH has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Anthony A. Marfin, MD, MPH has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
James J. Sejvar, MD has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Yanlin Tang, PhD, editorial consultant, has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Steven E. Weinberger, MD, FACP, Acting Editor, PIER, has stock holdings in Glaxosmithkline and Abbott.
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The information included herein should never be used as a substitute
for clinical judgment and does not represent an official position of
ACP. Because all PIER modules are updated regularly, printed web pages
or PDFs may rapidly become obsolete. Therefore, PIER users should
compare the date of the last update on the website with any printout
to ensure that the information being referred to is the most current
available.
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PIER is copyrighted (c) 2009 by the American College of Physicians,
190 N. Independence Mall West, Philadelphia, PA 19106-1572, USA.
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West Nile Virus Disease
> Diagnosis
