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Rationale:
- Some encephalitides (e.g., HSV) have distinct neurologic findings; acute flaccid paralysis syndrome and Guillain-Barré syndrome
have distinct findings, as well as treatment and course.
- There are no proven treatments for WNV meningitis, encephalitis, and acute flaccid paralysis syndrome.
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Evidence:
- Acute weakness associated with WNV infection has been variably attributed to myelitis, Guillain-Barré syndrome, or radiculopathy.
However, most cases of paralysis from WNV infection result from viral involvement of and damage to the lower motor neurons
of the spinal cord (anterior horn cells), resulting in acute flaccid paralysis (41).
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Comments:
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Amy V. Bode, MD, MSPH has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Anthony A. Marfin, MD, MPH has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
James J. Sejvar, MD has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Yanlin Tang, PhD, editorial consultant, has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Steven E. Weinberger, MD, FACP, Acting Editor, PIER, has stock holdings in Glaxosmithkline and Abbott.
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The information included herein should never be used as a substitute
for clinical judgment and does not represent an official position of
ACP. Because all PIER modules are updated regularly, printed web pages
or PDFs may rapidly become obsolete. Therefore, PIER users should
compare the date of the last update on the website with any printout
to ensure that the information being referred to is the most current
available.
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PIER is copyrighted (c) 2009 by the American College of Physicians,
190 N. Independence Mall West, Philadelphia, PA 19106-1572, USA.
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West Nile Virus Disease
> Consultation for Diagnosis
