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Rationale:
- CO is an odorless, colorless, tasteless gas that results from incomplete combustion of carbon.
- Any combustion appliance can produce elevated levels of CO if the device malfunctions or if ventilation is limited.
- Methylene chloride in paint strippers can be inhaled or absorbed through the skin and subsequently converted to CO by the
liver.
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Evidence:
- Electronic, audible CO detectors can prevent 50% of unintentional CO poisoning deaths as shown in this epidemiologic study
of 136 CO-related death(1).
- A review of national media services showed that cities with CO detector ordinances had a 0.4% fatality for all CO exposures,
whereas cities without CO detector requirements had fatality rates of 1.3% to 25% for exposed persons, suggesting that CO
detectors allow early recognition of exposure and prevent death (2).
- Case series of all CO-poisoning deaths in California from 1979 to 1988 showed significant ethanol use in 30% of cases (3).
- Case reports show that indoor combustion tools such as concrete saws (4), ice-surfacing machines (5), and forklift trucks (6) are associated with CO poisonings if not maintained and used properly.
- Case reports have shown that enclosed recreational vehicles such as boats (7) and single-engine aircraft (8) can lead to CO poisoning if not maintained and used properly.
- Case series studies have shown increased risk of CO poisoning during winter months (9), ice storms (10), and power outages (11).
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Comments:
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Jeffrey T. Chapman, MD has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Steven E. Weinberger, MD, FACP, Acting Editor, PIER, has stock holdings in Glaxosmithkline and Abbott.
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The information included herein should never be used as a substitute
for clinical judgment and does not represent an official position of
ACP. Because all PIER modules are updated regularly, printed web pages
or PDFs may rapidly become obsolete. Therefore, PIER users should
compare the date of the last update on the website with any printout
to ensure that the information being referred to is the most current
available.
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PIER is copyrighted (c) 2009 by the American College of Physicians,
190 N. Independence Mall West, Philadelphia, PA 19106-1572, USA.
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