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Recommendation
| Recognize the cost-effectiveness of nicotine replacement therapy and behavioral counseling for smoking cessation and the benefit they provide for a reduction in illness and death associated with smoking.
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Evidence:
- A meta-analysis of all smoking cessation interventions determined that the average cost per life saved was $1500 for one episode of advice (19). By comparison, the cost-effectiveness of dialysis is $46,322 (1994 dollars) per year of life saved (77).
- A cost-effectiveness analysis of nicotine patch, based on two meta-analyses, determined that the cost per quality-adjusted life year was between $4390 and $10,943 for men and between $4995 and $6983 for women. These values were sensitive to baseline cessation rates, physician counseling, and discounted rates. The baseline 1-year cessation rates used in this analysis were 2.5% for no intervention, 4% for physician counseling, and 7.9% for physician counseling plus nicotine patch (78).
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Comments:
- A simulation model based upon Swedish population data suggests that including bupropion SR as part of smoking cessation programs is cost-effective, and potentially cost-saving from the societal perspective, compared to the use of nicotine patch or gum (79).
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| Edward Ellerbeck, MD, MPH, editorial consultant, has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Kumanan Wilson, MD has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Steven E. Weinberger, MD, FACP, Acting Editor, PIER, has stock holdings in Glaxosmithkline and Abbott. |
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