Screening for Type 2 Diabetes > Effectiveness/Harms of Screening Tests Author: Lorraine Lipscombe, MD, FRCPC; Denice S. Feig, MD, MSc, FRCPC
Editorial changes - 2009-05-01
Author information and module status
Key Points
Population at Risk
Effectiveness/Harms of Screening Tests
Effectiveness/Harms of Early Treatment
Direct Evidence that Screening Reduces Adverse Outcomes
Timeline
Cost-Effectiveness
Patient Education
Referral/Consultation
Guidelines
Tables
References
Glossary
What's New
Patient Information
Additional Resources
Tools
Recommendation
Know that a 2-hour PG value of 200 mg/dL (11.1 mmol/L) after a 75-g OGTT is considered the gold standard for diagnosing diabetes mellitus.B

Evidence:

  • A 2-hour PG value of >=200 mg/dL (11.1 mmol/L) was shown to reflect a threshold separating subjects at increased risk of retinopathy (42; 43).
  • A 2-hour PG value of >=200 mg/dL (11.1 mmol/L) is associated with an increased risk of CAD and all-cause mortality (44).
  • The 2-hour PG is not as reliable as the FBG value. Intra-individual coefficients of variation when repeated 2 to 6 weeks apart were 16.7% for the 2-hour PG value vs. 6.4% for the FBG (45).

Comments:

  • None.

FAQs
Denice S. Feig, MD, MSc, FRCPC has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Lorraine Lipscombe, MD, FRCPC has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations. Sonal Singh, MD, editorial consultant, has no financial relationships with pharmaceutical companies, biomedical device manufacturers, or health-care related organizations.
Steven E. Weinberger, MD, FACP, Acting Editor, PIER, has stock holdings in Glaxosmithkline and Abbott.

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